Rivaroxyban- S- isomer

Rivaroxyban-S-isomer is a stereoisomeric variant of the parent compound Rivaroxyban, characterized by a chiral center at the 2-position of its tetrahydroisoquinoline core, adopting the S-configuration. The molecule features an aromatic amine moiety, a pyridine ring, and a substituted cyclohexyl group, with stereochemical differences influencing its pharmacokinetic profile. This impurity arises via partial racemization during synthetic resolution processes, resulting in enantiomeric excess deviations. It serves as a critical HPLC reference standard for enantiomeric purity analysis in Rivaroxyban drug substance characterization.