ABC00825OM

(S)-Lercanidipine Hydrochloride

(S)-Lercanidipine Hydrochloride is the enantiomerically pure hydrochloride salt of the calcium channel blocker Lercanidipine, featuring a chiral dihydropyridine core substituted with a nitrophenethyl ester and a 2-(3-butenyloxy)ethyl side chain. The (S)-configuration at the stereocenter differentiates it from the parent racemic drug, introducing distinct stereochemical interactions. This impurity arises during enantioselective synthesis or resolution processes. It serves as an HPLC reference standard for enantioselective purity profiling in pharmaceutical quality control.

On Request
Molecular Formula C36H42ClN3O6
Molecular Weight 648.2000
CAS Number 184866-29-3 โœ“ Verified
PubChem CID 9874314 โ†—
Purity N/A
Product Type API Impurity
Parent Drug Lercanidipine
Lead Time On Request
IUPAC Name 5-O-[1-[3,3-diphenylpropyl(methyl)amino]-2-methylpropan-2-yl] 3-O-methyl (4S)-2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate;hydrochloride

๐Ÿ“ Synonyms

(S)-Lercanidipine Hydrochloride 184866-29-3 (S)-Lercanidipine HCl (+)-Lercanidipine hydrochloride (S)-Lercanidipine (hydrochloride) Lercanidipine hydrochloride, (S)- 4613R830EU (S)-3-(1-((3,3-Diphenylpropyl)(methyl)amino)-2-methylpropan-2-yl) 5-methyl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate hydrochloride 5-O-[1-[3,3-diphenylpropyl(methyl)amino]-2-methylpropan-2-yl] 3-O-methyl (4S)-2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate;hydrochloride 3,5-Pyridinedicarboxylic acid, 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-, 3-(2-((3,3-diphenylpropyl)methylamino)-1,1-dimethylethyl) 5-methyl ester, hydrochloride (1:1), (4S)-

๐Ÿ”ฌ Chemical Identifiers

CC1=C([C@@H](C(=C(N1)C)C(=O)OC(C)(C)CN(C)CCC(C2=CC=CC=C2)C3=CC=CC=C3)C4=CC(=CC=C4)[N+](=O)[O-])C(=O)OC.Cl
InChI=1S/C36H41N3O6.ClH/c1-24-31(34(40)44-6)33(28-18-13-19-29(22-28)39(42)43)32(25(2)37-24)35(41)45-36(3,4)23-38(5)21-20-30(26-14-9-7-10-15-26)27-16-11-8-12-17-27;/h7-19,22,30,33,37H,20-21,23H2,1-6H3;1H/t33-;/m0./s1
WMFYOYKPJLRMJI-WAQYZQTGSA-N

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