ABC01306CX

sofosbuvir Tri benzoyl fluoro cytidine

Sofosbuvir Tri benzoyl fluoro cytidine is a fluorinated, tri-benzoylated nucleoside derivative structurally related to the antiviral agent sofosbuvir. It features a 1-(2-deoxy-2-fluoro-ฮฒ-D-ribofuranosyl)-1H-pyrimidin-2-one core substituted with three benzoyl groups at the 5-hydroxy, 3-hydroxy, and 2'-hydroxy positions. This compound arises as a synthetic intermediate during sofosbuvir production via benzoyl protection of the fluoro-cytidine precursor. It serves as an HPLC reference standard for quantifying benzoylation-related impurities in sofosbuvir active pharmaceutical ingredient batches.

On Request
Molecular Formula C31H26FN3O7
Molecular Weight 571.6000
CAS Number 817204-32-3 โœ“ Verified
PubChem CID 11330583 โ†—
Purity N/A
Product Type API Impurity
Parent Drug Sofosbuvir
Lead Time On Request
IUPAC Name [(2R,3R,4R,5R)-5-(4-benzamido-2-oxopyrimidin-1-yl)-3-benzoyloxy-4-fluoro-4-methyloxolan-2-yl]methyl benzoate

๐Ÿ“ Synonyms

817204-32-3 Cytidine, N-benzoyl-2'-deoxy-2'-fluoro-2'-methyl-, 3',5'-dibenzoate, (2'R)- DTXSID901144030 (2R,3R,4R,5R)-5-(4-benzamido-2-oxopyrimidin-1(2H)-yl)-2-(benzoyloxymethyl)-4-fluoro-4-methyltetrahydrofuran-3-yl benzoate RefChem:581428 DTXCID701575629 807-677-9 (2R,3R,4R,5R)-5-(4-Benzamido-2-oxopyrimidin-1(2H)-yl)-2-((benzoyloxy)methyl)-4-fluoro-4-methyltetrahydrofuran-3-yl benzoate MFCD23106344 (2'R)-N-Benzoyl-2'-deoxy-2'-fluoro-2'-Methylcytidine 3',5'-dibenzoate

๐Ÿ”ฌ Chemical Identifiers

C[C@]1([C@@H]([C@H](O[C@H]1N2C=CC(=NC2=O)NC(=O)C3=CC=CC=C3)COC(=O)C4=CC=CC=C4)OC(=O)C5=CC=CC=C5)F
InChI=1S/C31H26FN3O7/c1-31(32)25(42-28(38)22-15-9-4-10-16-22)23(19-40-27(37)21-13-7-3-8-14-21)41-29(31)35-18-17-24(34-30(35)39)33-26(36)20-11-5-2-6-12-20/h2-18,23,25,29H,19H2,1H3,(H,33,34,36,39)/t23-,25-,29-,31-/m1/s1
MXEQSUUFNWPUJH-RDWHIKKYSA-N

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