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Spironolactone Impurity A

Spironolactone Impurity A features a steroid nucleus with a spirolactone moiety, differing from the parent drug by a specific structural modification. It contains a sulfonamide group and multiple chiral centers, contributing to its unique chemical properties. This impurity is used as an HPLC reference standard.

On Request
Molecular Formula C24H30O4S
Molecular Weight 414.6000
CAS Number 132458-33-4 ✓ Verified
PubChem CID 14748917 ↗
Purity N/A
Product Type API Impurity
Parent Drug Spiranolactone
Lead Time On Request
IUPAC Name S-[(7R,8R,9S,10R,13S,14S,17R)-10,13-dimethyl-3,5'-dioxospiro[2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthrene-17,2'-furan]-7-yl] ethanethioate
Official Reference Standards
Std Catalog # Quantity Price
USP 1619028 ↗ 30 mg USD 1711.00

📝 Synonyms

20,21-Dehydro Spironolactone Spironolactone EP impurity A UNII-NE78JL28MG delta20-Spironolactone 132458-33-4 NE78JL28MG (2R)-3,4-Dihydro-5H-spiro(androst-4,6-diene-17,2-furan)-3,5-dione. (2'R)-7alpha-(Acetylthio)-5'H-spiro(androst-4-ene-17,2'-furan)-3,5'-dione S-[(7R,8R,9S,10R,13S,14S,17R)-10,13-Dimethyl-3,5'-dioxospiro[2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthrene-17,2'-furan]-7-yl] ethanethioate Spironolactone impurity A [EP]

🔬 Chemical Identifiers

CC(=O)S[C@@H]1CC2=CC(=O)CC[C@@]2([C@@H]3[C@@H]1[C@@H]4CC[C@]5([C@]4(CC3)C)C=CC(=O)O5)C
InChI=1S/C24H30O4S/c1-14(25)29-19-13-15-12-16(26)4-8-22(15,2)17-5-9-23(3)18(21(17)19)6-10-24(23)11-7-20(27)28-24/h7,11-12,17-19,21H,4-6,8-10,13H2,1-3H3/t17-,18-,19+,21+,22-,23-,24+/m0/s1
KCWOLKZQDUPWRC-ZHYRCANASA-N

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