Taurodeoxycholicacid (Crude) is a sodium salt of a taurine-conjugated bile acid derivative, structurally derived from deoxycholic acid via amidation with taurine at the C-24 position. It features a steroid nucleus with a 5ฮฒ-cholan-24-oic acid backbone, three hydroxyl groups at C-3, C-7, and C-12, and a sulfonate group from taurine conjugation. As an API impurity, it arises from incomplete conjugation during parent drug synthesis. This crude form serves as an HPLC reference standard for quantifying conjugated bile acid impurities in pharmaceutical formulations.
On RequestC[C@H](CCC(=O)NCCS(=O)(=O)[O-])[C@H]1CC[C@@H]2[C@@]1([C@H](C[C@H]3[C@H]2CC[C@H]4[C@@]3(CC[C@H](C4)O)C)O)C.[Na+]
InChI=1S/C26H45NO6S.Na/c1-16(4-9-24(30)27-12-13-34(31,32)33)20-7-8-21-19-6-5-17-14-18(28)10-11-25(17,2)22(19)15-23(29)26(20,21)3;/h16-23,28-29H,4-15H2,1-3H3,(H,27,30)(H,31,32,33);/q;+1/p-1/t16-,17-,18-,19+,20-,21+,22+,23+,25+,26-;/m1./s1
YXHRQQJFKOHLAP-FVCKGWAHSA-M