ABC01390BM

Thiorphan

Thiorphan is a thiazoline-based peptidomimetic inhibitor featuring a sulfonamide-linked nitrophenyl ester moiety. Its core structure comprises a five-membered thiazoline ring conjugated to a benzene sulfonamide group, with a para-nitro substituent on the aromatic ring. This compound represents the pharmacophore of the parent drug, optimized for angiotensin-converting enzyme (ACE) inhibition. It serves as an HPLC reference standard for quantitative analysis of ACE inhibitor formulations.

On Request
Molecular Formula C12H15NO3S
Molecular Weight 253.3200
CAS Number 76721-89-6 ✓ Verified
PubChem CID 3132 ↗
Purity N/A
Product Type API
Parent Drug Thiorphan
Lead Time On Request
IUPAC Name 2-[(2-benzyl-3-sulfanylpropanoyl)amino]acetic acid

📝 Synonyms

THIORPHAN dl-thiorphan 76721-89-6 NSC-727676 B79L7B5X3Z Glycine, N-(2-(mercaptomethyl)-1-oxo-3-phenylpropyl)-, (+-)- Tiorphan XJ8Z52GK3X (3-Mercapto-2-benzylpropionyl)glycine RefChem:897915

🔬 Chemical Identifiers

C1=CC=C(C=C1)CC(CS)C(=O)NCC(=O)O
InChI=1S/C12H15NO3S/c14-11(15)7-13-12(16)10(8-17)6-9-4-2-1-3-5-9/h1-5,10,17H,6-8H2,(H,13,16)(H,14,15)
LJJKNPQAGWVLDQ-UHFFFAOYSA-N

Related Products