Tolterodine Diol Acetate Impurity

Tolterodine Diol Acetate Impurity is a degradation product formed via hydrolytic cleavage of the ester linkage in Tolterodine, followed by acetylation of the resulting diol functionality. The compound retains the 1,1-dimethylethyl and 4-methylpiperidin-1-yl substituents of the parent drug but features a fully acetylated diol moiety at the propanoyl backbone. This impurity exhibits enhanced hydrolytic stability compared to the parent API and is used as an HPLC reference standard for monitoring oxidative degradation pathways in Tolterodine formulations.