Trazodone USP Related Compound C

Trazodone USP Related Compound C is a chlorinated tetracyclic derivative featuring a substituted phthalazine core with an additional chloro group at the 3-position of the benzene ring and a dimethylaminoethyl side chain. Its structural divergence from trazodone includes a second chlorine substitution and an extra nitrogen in the heterocyclic framework, resulting in altered electronic properties. This compound arises as a synthetic byproduct during API production via nucleophilic aromatic substitution pathways. It serves as a critical HPLC reference standard for impurity profiling in trazodone formulations.