Vilazidone cyano O-alkyl impurity

Vilazidone cyano O-alkyl impurity is a synthetic byproduct arising from alkylation at the piperazine oxygen atom of the parent drug, featuring a retained cyano group and an alkyl chain substitution at the O-position. This impurity exhibits structural similarity to vilazidone but with altered hydrophobicity and steric hindrance due to the O-alkyl modification. It serves as a critical HPLC reference standard for quantifying process-related impurities in vilazidone API synthesis.