Sulfociproflaxacin

Sulfociproflaxacin is a sulfonated fluoroquinolone derivative characterized by a quinolone core substituted with a 1-cyclopropyl, 6-fluoro, and 8-sulfamoyl piperazine moiety. The molecule incorporates a carboxylic acid at position 3 and a fluorine atom at position 6, with the sulfonic acid group (-SO3H) appended to the piperazine ring, distinguishing it from the parent drug. This structural modification enhances polarity and alters binding affinity to bacterial topoisomerases. It functions as a specific oxidative degradation byproduct of ciprofloxacin under acidic conditions.